פרופ' יעקב אשכנזי

Deputy Director of In Vitro Fertilization Unit

Department of Obstetrics and Gynecology,

Rabin Medical Center (Beilinson Hospital)

A. EDUCATION

 

1974                Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

1973                M.D. degree."Magna Cum Laude"

                        Doctoral Dissertation:

                        Vitamin E in unsaturated fatty acids

                        Supervisors:  Professor I. Tamir.

 

1977-1983       Specialization Certification in Obstetrics-Gynecology

 

1981-1982       Basic science trainings in in vitro fertilization program and reproductive endocrinology, Tel Hashomer Medical Center,

Tel Hashomer, Israel.

                        Thesis :Hamster penetration assay of normal sperm  undergoing IVF.

  

 

 

B.  FURTHER STUDIES

 

1983-1984       Further specialization and close collaboration with the in vitro fertilization program and reproductive endocrinology, Tel Hashomer Medical Center,

Tel Hashomer, Israel.

 

1984-1985       Fertility Institute and IVF program, Vienna, Austria

                        (Directors:  Dr W. Feichtinger and Dr P. Kemeter).

 

 

 

C.  ACADEMIC EXPERIENCE

 

1978                Tutor to 6th year medical students in Obstetrics and Gynecology, Endocrinology and Reproduction, Israeli and American students of the Israel Branch of New York State Medical School, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

 

1978                Lecturer in Obstetrics and Gynecology, Endocrinology and Reproduction, Israeli and American students of the Israel Branch of New York State Medical School, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

 

1980                Member of the Examination Board in Obstetrics and Gynecology of senior medical students.

 

1982-date        Lecturer in postgraduate courses for residents in Obstetrics and

Gynecology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

 

1989                Lecturer in Obstetrics-Gynecology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

 

1.1.1996-date  Senior Lecturer in Obstetrics-Gynecology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

 

 

 

D.  CLINICAL EXPERIENCE

 

1972                Internship, Municipal Hospital of Tel Aviv, Tel Aviv University, Tel Aviv,                       Israel.

 

1977-1983       Specialization in Obstetrics-Gynecology, with subspecialty in Reproductive Endocrinology, Golda Meir Medical Center (Hasharon Hospital), Petah Tiqwa, Israel.

                        Head:  Professor Jack Goldman.

 

1980                Head of Male Infertility Unit, Golda Meir Medical Center (Hasharon Hospital), Petah Tiqwa, Israel.

 

1983-1984       Endocrinology and IVF, Tel Hashomer Medical Center,

Tel Hashomer, Israel

                        Head:  Professor M. Mashiach.

 

1983                Senior Physician, Department of Obstetrics and Gynecology, Golda Meir Medical Center (Hasharon Hospital), Petah Tiqwa, Israel.

 

1984                Fellowship in In Vitro Fertilization Program of Fertility Institute, Vienna, Austria.

 

1988                Specialization in diagnostic and operative hysteroscopy Hospital Palais       Royal           Paris-professor Hamou.

.

1997-2003      Acting Director of the In Vitro Fertilization Unit Department of Obstetrics and Gynecology, Golda Meir Medical Center (Hasharon Hospital), Petah Tiqwa, Israel.

 

2004-To date  Deputy Director of In Vitro Fertilization Unit Department of Obstetrics and Gynecology, Rabin Medical Center (Beilinson Hospital), Petah Tiqwa, Israel.

LIST OF PUBLICATIONS (2008-2013)

 

B.1.  ORIGINAL ARTICLES

 

 

76.       Yoeli R, Orvieto R, Ashkenazi J, Shelef M, Ben-Rafael Z, Bar-Hava I.

.           Comparison of embryo quality between intracytoplasmic sperm injection and in vitro  fertilization in sibling oocytes.

J Assist Reprod Genet. 2008;25(1):23-8. Epub 2008 .

           (OBSTETRICS & GYNECOLOGY 50/61, IF1.123)

  

77.       R. Orvieto, R. Nahum, S. Meltcer, R. Homburg, J. Rabinson, E.Y. Anteby, J. Ashkenazi.

Ovarian stimulation in polycystic ovary syndrome: the role of body mass index.

 RBM Online 2009;18(3): 333-336

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)

78.     * J. Rabinson,* J. Ashkenazi, R. Homburg, S. Meltcer, E.Y. Anteby,R. Orvieto.

Repeated in-vitro fertilization cycle attempts in patients undergoing controlled     ovarian hyperstimulation using GnRH-antagonists

Fertil Steril 2009;91:1473-5

*(both authors contributed equally to the study)

REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

79.       R. Orvieto, S. Meltcer, R. Homburg, R. Nahum, J. Rabinson, J. Ashkenazi.

What is the preferred GnRH-analogue for polycystic ovary syndrome patients undergoing controlled ovarian hyperstimulation for in-vitro fertilization?

            Fertil Steril 2009;91:1466-8.

           (REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

80.       J. Ashkenazi, I Bar-Hava, S Meltcer, J Rabinson, EY Anteby, R Orvieto.                            

The possible influence of increased body mass index on the clinical efficacy of standard human chorionic gonadotropin dosage.

Clin Exp Obstet Gynecol 2009;36(1):20-2

 

81.       R. Orvieto,  R. Nahum, J. Rabinson, EY. Anteby, S. Meltcer, J.Ashkenazi.

            The influence of body mass index on in-vitro fertilization outcome.

            Int J Gynecol Obstet 2009;104(1):53-5.

            (OBSTETRICS & GYNECOLOGY 45/61, IF 1.228)

 

82.       R. Orvieto,  R. Nahum, J. Rabinson, J.Ashkenazi, EY. Anteby, S. Meltcer.

            Follitropin- (Gonal-F) versus Follitropin- (Puregon) in Controlled Ovarian Hyperstimulation for in-Vitro Fertilization: Is there any difference?

            Fertil Steril 2009;91:1522-5.

            (REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

83        Pinkas H, Sapir O, Avrech OM, Ben-Haroush A, Ashkenazi J, Fisch B, Farhi J.

The effect of oral contraceptive pill for cycle scheduling prior to GnRH-antagonist          protocol on IVF cycle parameters and pregnancy outcome.

            J Assist Reprod Genet. (1):29-33. Epub 2008

            (OBSTETRICS & GYNECOLOGY 50/61, IF1.123)

 

 

84.    * J.Farhi.,*A. Ben Haroush, N. Areus, H.Pinkas, O.Sapir, B.Fisch. J, Ashkenazi.

High serum oestradiol concentrations in IVF cycles increase the risk of  pregnancy complications related to abnormal placentation

*Dr Farhi and Dr Ben-Haroush equally contributed to the study and both are    first authors.

RBM Online 2010 Sep;21(3):331-7

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)

 

85       High quality embryos retain their implantation capability in overweight women

* J.Farhi.,*A. Ben Haroush, , O.Sapir, B.Fisch. J, Ashkenazi.

RBM Online 2010 Nov;21(5):706-11.

*Dr Farhi and Dr Ben-Haroush equally contributed to the study and both are    first authors.

 

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)

 

86        High-quality embryos maintain high pregnancy rates in passive smokers but

      not  in  active smokers

     *A. Ben Haroush,* J Ashkenazi, O. Sapir, B. Fisch, J. Farhi.

*(both authors contributed equally to the study)

           Reprod Biomed Online. 2011 Jan;22(1):44-9.

           

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)

 

 

ARTICLES SUBMITTED FOR PUBLICATION

           

 

1. J. Ashkenazi, S Meltcer, J Rabinson,R. Homburg, EY Anteby, R Orvieto.                            
2. The role of GnRH-analogues used in elderly (>38 yrs) patients undergoing controlled ovarian hyperstimulation for IVF.

              Clin Exp Obstet Gynecol.

                        

 

CHAPTERS IN BOOKS

 

1         J,Ashkenazi, D.Feldberg, D.Dicker , A.Yeshaya, J.Goldman.

The impact of spermatic vein ligation on the male factor in IVF-ET and its relation to       testosterone levls before and after operation.

            In: Year Book of Infertility

             D.R. Mishell (Ed.)

            Mosby-Year Book Inc,Chicago,USA,pp.130-131,1990.

 

2          D.Dicker,J.Goldman,D.Feldberg,J.Ashkenazi,M.Shelef,I.Levy.

            Age and pregnancy rates in in-vtro fertilization.

            In: Year Book of Infertility

            D.R. Mishell (Ed.)

            Year Book of infertility.Mosby-Year Book Inc 1991

 

3.         D. Dicker, J. Goldman, J. Ashkenazi, D. Feldberg.

Combination of long and short term GnRH analogue protocol:  a new therapeutic approach to persistent high progesterone levels in IVF cycles.

            In:  The Basic Science of GnRH Analogues

            B. Lunenfeld (Ed.)

Parthenon Publishing Group, Lancs, England 1991.

 

4.         D. Dicker, J. Goldman, J. Ashkenazi, D. Feldberg.

The value of pre-IVF treatment with GnRH analogue in severe endometriosis.

            In:  The Basic Science of GnRH Analogues

            B. Lunenfeld (Ed.)

            Parthenon Publishing Group, Lancs, England 1991.

 

5.         R. Homburg,  J. Ashkenazi, D. Avidan.

The endocrinology of pregnancy, labour and puerperium.

            In:  Clinical Reproductive Endocrinology

            G. M. Prelevic (Ed.)

Lovika Belgrade, Yugoslavia, pp. 181-198, 1992.

 

 

6.         R. Homburg, D. Berkovitz, T. Levy, D. Feldberg, J. Ashkenazi,

Z. Ben-Rafael.

In vitro fertilization and embryo transfer for treatment of infertility associated with polycystic ovary syndrome

 

In:  Year Book of Infertility

D.R. Mishell (Ed.)

Mosby Year Book Inc., Chicago, 1994.

 

 

 

 

 

 

MOST IMPORTANT PUBLICATIONS

(Since my last academic nomination)

 

 

 49.      J. Ashkenazi^(pi), R. Orvieto^(c), R. Gold-Deutch^(s), D. Feldberg^(c), D. Dicker^(c), I. Voliovitch^(c), Z. Ben-Rafael^{(c )} .

The impact of women's age and sperm parameters on fertilization rates in IVF cycles.

Eur J Obstet Gynecol Reprod Biol 66:155-159, 1996.

            (REPRODUCTIVE BIOLOGY 22/25 ,IF 1.432)

52.       I. Bar-Hava^(pi), J. Ashkenaz^(c)i, M. Shelef^(t), A. Schwartz^(t), M. Brengauz^(t), D. Feldberg^(c), R. Orvieto, ^(c) Z. Ben-Rafae^(c)l.

Morphology and clinical outcomes of embryos after in-vitro fertilization are superior to those after intracytoplasmic sperm injection.

Fertil Steril 68:653-657, 1997.

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

57.       J. Ashkenazi^(pi), I. Bar-Hava^(c), J. Farhi^(c), T. Levi^(c), D. Feldberg^(c), R. Orvieto^(c), Z. Ben-Rafael^(c).

The role of purified follicular stimulating hormone therapy in the male partner before intracytoplasmic sperm injection.

Fertil Steril 72:670-673, 1999

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

59.       Z. Ben Rafael^(pi), J Farhi^(c), D. Feldberg^(c), B. Bartoov^(t), M. Kovo^(c), F. Eltes^(t), J   Ashkenazi^(pi).

Follicle-stimulating hormone treatment for men with idiopathic oligoteratoasthenozoospermia before in vitro fertilization: the impact on sperm microstructure and fertilization potential.
Fertil Steril 73(1):24-30, 2000.

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

62.       J. Ashkenazi^(pi), R. Yoeli^(c), R. Orvieto^(c), J. Shalev^(c), Z. Ben-Rafael^(c),

I. Bar-Hava^(c).

Double (consecutive) transfer of early embryos and blastocysts aims and results.

Fertil Steril 74:936-40, 2000.

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

77.       R. Orvieto^(pi), R. Nahum^(c), S. Meltcer^(c), R. Homburg^(c), J. Rabinson^(c), E.Y. Anteby^(c), J. Ashkenaz^(pi)i.

Controlled Ovarian Hyperstimulation in Polycystic Ovary Syndrome Patients:

  The Role of Body Mass Index

 RBM Online 2009;18(3): 333-336

(REPRODUCTIVE BIOLOGY 9/25, IF 2.84 )

.

 

78.     * J. Rabinson^(pi),* J. Ashkenaz^(pi)i, R. Homburg^(c), S. Meltcer^(c), E.Y. Anteby^(c),   R. Orvieto^(c).

Repeated in-vitro fertilization cycle attempts in patients undergoing controlled ovarian hyperstimulation using GnRH-antagonists

Fertil Steril). 2009;91:1473-5

*(both authors contributed equally to the study)

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

79        R. Orvieto^(pi), S. Meltcer^(c), R. Homburg^(c), R. Nahum^(c), J.Ashkenazi^(pi).

What is the preferred GnRH-analogue for polycystic ovary syndrome patients undergoing controlled ovarian hyperstimulation for in-vitro fertilization?

Fertil Steril 2009;91:1466-8

(REPRODUCTIVE BIOLOGY 2/25, IF 4.167 )

 

81.       R. Orvieto^(pi) ,  R. Nahum^(c), J. Rabinson^(c), E.Y. Anteby^(c), S. Meltcer^(c), J. Ashkenazi^(pi).  

            The influence of body mass index on in-vitro fertilization outcome.

             Int J Gynecol Obstet 2009;104(1):53-5

            (OBSTETRICS & GYNECOLOGY 31/60, IF 1.114 )

 

84.    * J.Farhi.,*A. Ben Haroush, N. Areus, H.Pinkas, O.Sapir, B.Fisch. J, Ashkenazi.

High serum oestradiol concentrations in IVF cycles increase the risk of  pregnancy complications related to abnormal placentation

*Dr Farhi and Dr Ben-Haroush equally contributed to the study and both are    first authors.

RBM Online 2010

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)

 

85       * J.Farhi ^pi).,*A. Ben Haroush ^pi), O.Sapir^(c), B.Fisch^(c) J.Ashkenazi ^pi).

           High quality embryos retain their implantation capability in overweight women                       

*Dr Farhi and Dr Ben-Haroush equally contributed to the study and both are      first authors.

 RBM Online 2010

(REPRODUCTIVE BIOLOGY 8/25, IF 2.954)