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Attias-Geva, Z., Bentov, I., Kidron, D., Amichay, K., Sarfstein, R., Fishman, A., Bruchim, I. and Werner, H. p53 regulates insulin-like growth factor-I receptor gene expression in uterine serous carcinoma and predicts responsiveness to an IGF-IR-directed targeted therapy. (2011). Eur. J. Cancer, Epub ahead of print Oct 25.
Sarfstein, R., Bruchim, I., Fishman, A. and Werner, H. The mechanism of action of the histone deacetylase inhibitor vorinostat involves interactions with the insulin-like growth factor signaling pathway. (2011). PLoS ONE 6(9):e24468.
Attias-Geva, Z., Bentov, I., Ludwig, D.L., Fishman, A., Bruchim, I. and Werner, H. Insulin-like growth factor-I receptor targeting with monoclonal antibody cixutumumab (IMC-A12) inhibits IGF-1 action in endometrial cancer cells. (2011). Eur. J. Cancer 47:1717-1726.
Yehezkel, E., Weinstein, D., Simon, M., Sarfstein, R., Laron, Z. and Werner, H. Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor. (2010). Diabetologia 53:2667-2675.
Werner, H. and Bruchim, I. Basic and clinical significance of IGF-I-induced signatures in cancer. (2010). BMC Medicine Jan 5; 8:2.
Schayek, H., Bentov, I., Sun, S., Plymate, S.R. and Werner, H. Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene
and transcriptional suppression of the insulin-like growth factor-I receptor gene. (2010). Exp. Cell Res. 316:1479-1488.
Sarfstein, R., Belfiore, A. and Werner, H. Identification of IGF-I receptor gene promoter-binding proteins in estrogen receptor (ER)-positive and ER-depleted breast cancer cells. (2010). Cancers (Basel) 2:233-261.
Schayek, H., Haugh, K., Sun, S., True, L.D., Plymate, S.R. and Werner, H. Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor-I receptor gene transcription in an androgen receptor-dependent manner. (2009). Clin. Cancer Res. 15:1558-1565.