Bionano Genome Mapping: High-Throughput Mapping of Structural Variation in Cancer and Genetic Disease

The BioMed@TAU Personalized Epigenomics Research Hub invites you to

 

"Bionano Genome Mapping: High-Throughput Mapping of Structural Variation in Cancer and Disease.”

 

 

The lecture will take place on Wednesday, December 5, 2018 from 12:30-14:00 in the Sackler School of Medicine, 120 a+b 

 

12:30 Refreshments

 

13:00 Lecture 

 

The diagnostic yield in genetic disease has seen very little improvement over the last few decades, despite the introduction of whole genome sequencing. The promise of personalized medicine in cancer remains elusive, because no single technology can comprehensively detect all the rearrangements in the cancer genome.
 
Bionano Genomics’ platform for whole genome mapping offers an extremely long-read technology, providing unmatched sensitivity to detect structural variation. Our de novo maps can resolve complex repetitive regions, identify Copy Number Variations, and elucidate genome-wide structural variation like balanced/unbalanced translocations, inversions, and indels with much higher sensitivity and precision than sequencing-based methods. 
 
Examples will be presented of how Bionano’s platform is helping provide a molecular diagnosis for patients with undiagnosed genetic disorders, and how it elucidates genomic rearrangements in cancer that are missed by NGS and cytogenetic methods. 

 

Hosted by: BioMed@TAU, GAL, and SICF

 

Attendance is free, let us know if you are joining RSVP here

 

Check out our new website for other upcoming events! https://www.biomedtau.com