פרופ' ניצה גולדנברג

Research Grants (last 3 years)

2008-2011       Ministry of Health, Chief Scientist’s Office. Intravitreal injection of adult

                        bone marrow derived stem cells to developing retina of newborn mice

2008-2012       Israel Scientific Foundation (ISF). "Adult bone marrow derived stem cells mediate repair of retinal injury".

2010-2011       The Claire and Amedee Maratier Institute for the study of visual disorders and  blindness, Tel Aviv University “Intravitreal injection of BMSC to neonates eyes”

2012-2016       Israel Science Foundation (ISF). “Mobilization and Growth Factors Affect Homing and the Differentiation of Adult Bone Marrow Derived Stem Cells in Injured and Developing Retina“.

1.            O. Dratviman-Storobinsky,  Y. Cohen,  S. Frenkel, J. Pe’er,  N. Goldenberg-Cohen.  Lack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva.  Invest Ophthalmic Vis Sci. 2010;51:6180 – 6182.

2.            M. Ehrenberg,  O. Dratviman, BR. Avraham-Lubin, N. Goldenberg-Cohen. C1367T Polymorphism in the WRN gene has no association with senile cataract in the Israeli population. Molecular Vision. 2010; 16:1771-1775

3.            N. Assia, N. Goldenberg-Cohen, G. Rechavi, N. Amariglio, Y. Cohen.

Mutation Analysis of the ferritin L-chain Gene in the Age-Related Cataract.

Molecular Vision. 2010; 16: 2487–2493.

4.            S. Itzkovitz S, N. Goldenberg-Cohen, J. Stein, I. Yaniv, D.L. Farkas, N. Askenasy. β-cell neogenesis: experimental considerations adult in stem cell differentiation. Stem cells and development. 2011 Apr;20(4):569-82.

5.            N. Goldenberg-Cohen, M. Gabbay, O. Dratviman-Storobinsky, E. Reich, R. Axer-Siegel, D. Weinberger,U. Gabbay. Does haptoglobin genotype affect early onset of diabetic retinopathy in patients with type 2 diabetes? Retina, 2011 Sep;31(8):1574-1580.

6.            S. Itzkovitz S, N. Goldenberg-Cohen, J. Stein, I. Yaniv, I. Fabian, N. Askenasy. Elutriated stem cells derived from the adult bone marrow differentiate into insulin producing cells in vivo and reverse chemical diabetes.  Stems cell and development. 21(1):86-96, 2012.

7.            BR. Avraham-Lubin,  O. Dratviman-Storobinsky,  S. Dadon-Bar El, M. Hasanreisoglu, N. Goldenberg-Cohen. Neuroprotective Effect of Hyperbaric Oxygen Therapy on Anterior Ischemic Optic Neuropathy.

Front Neurol. 2011 Apr 13;2:23.

8.            N. Goldenberg-Cohen, O. Dratviman-Storobinsky,  S. Dadon Bar El,  Y. Cheporko, and  E.  Hochhauser. Protective effect of bax ablation against retinal ischemia/reperfusion injury in transgenic mice.

               Journal of Neuroophthalmology. 2011 :31 (4) 331–338.

9.            Y. Cohen, N. Goldenberg-Cohen, B. Shalomon , T. Shani , S. Oren, N. Amariglio, A. Shnaiderman-Shapiro, R. Yahalom, I. Kaplan, A. Hirshberg. Mutational analysis of PTEN/PIK3CA/AKT pathway in oral squamous cell carcinoma. Oral Oncology. 2011;47(10):946-50.

10.          V. Gaydar, D. Ezrachi, O. Dratviman-Storobinsky, S. Hofstetter, BR. Avraham-Lubin, N. Goldenberg-Cohen. Reduction of Apoptosis in Ischemic Retinas of Two Mouse Models Using Hyperbaric Oxygen Treatment. Invest Ophthalmic Vis Sci 2011;29;52(10):7514-22.

11.          N. Goldenberg-Cohen, BR. Avraham-Lubin, T. Sadikov,  RS.   Goldstein, N. Askenasy. Primitive Stem Cells Derived from Bone Marrow Express Glial and Neuronal Markers in Injured Retina and Support  Recovery from Ischemic and Mechanical Injury. Stem cells development  2012.   Jun 10;21(9):1488-500.

12.          T. Sadikov, A,J. Simon, B.R. Avraham-Lubin, O.Dratviman-Storobinsky, Y. Cohen, N. Goldenberg-Cohen. C1824T mutation in the LMNA gene has no association with senile cataract in the Israeli population. Neurobiology of Aging 2012, 33:1487.e15–1487.e19,

13.          N. Goldenberg-Cohen, A. Raiter, V. Gaydar, O. Dratviman-Storobinsky,  T. Goldstein, A. Weizman, and  B. Hardy. Peptide-binding heat shock protein GRP78 protects neurons from hypoxia-induced apoptosis. Apoptosis.  2011 17(3):278-288.

14.          Dratviman-Storobinsky, Y. Cohen, S. Frenkel, E. Merhavi-Shoham,  S. Dadon-Bar El, N. Binkovsky,  J. Pe'er, N. Goldenberg-Cohen. The role of RASSF1A in uveal melanoma. Invest Ophthal Vis Sci 2012, 53:2611–2619.

15.          Y. Laviv, H. Toledano, S. Michowiz, O. Dratvima-Storobinsky, S. Fichman-Horn, E. Kagnovski, N. Goldenberg-Cohen.  BRAF, GNAQ, and GNA11 mutations and copy number in pediatric low-grade glioma. FEBS open bio, 2012, 2:129–134.

16.          N. Goldenberg-Cohen, B.R. Avraham-Lubin, T. Sadikov, N. Askenasy

               VEGF induces neural and astrocytic differentiation and angiogenesis in bone marrow-derived stem cells and promotes microglia conversion following  mobilization with GM-CSF. Stem Cell Reviews and Reports. In press.

17.          Y. Cohen; N. Goldenberg-Cohen; S.  Akrish, T.  Shani, N.  Amariglio; O. Dratviman-Storobinsky; I.  Kaplan; I. Barshack, A. Hirshberg. BRAF and GNAQ mutations in melanocytic tumors of the oral cavity. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology. In press.