פרופ' יגאל דניאל [דני] כהן

ביה"ס לבריאות הציבור סגל אקדמי בכיר
ניווט מהיר:
פרופ' יגאל דניאל [דני] כהן
טלפון פנימי: 03-6407081
פקס: 03-6409868


Professor, Epidemiology and Preventive Medicine, School of Public Health, Tel Aviv University

Chair, Middle East Consortium Middle East Consortium on Infectious Disease Surveillance (MECIDS)

Diana & Stanley Steyer Chair of Cancer Prevention and Control

Co-Director, Summer Institute of Advanced Epidemiology and Preventive Medicine, Tel Aviv University

Head, Tiberio Swartz Research Forum on Epidemiology of Infectious Diseases and Biosecurity



Professor Daniel (Dani) Cohen joined Tel Aviv University (TAU) for a full-time academic position in 2002 and has been a full Professor since 2007. Previously, he served in the Israel Defense Forces for many years and was the Director of the Infectious Diseases Research Institute in the Medical Corps. Prof. Cohen served as the Head of Tel Aviv University School of Public Health for 6 years, after serving 4 years as Chair of the Department of Epidemiology and Preventive Medicine. Prof. Cohen is currently the Diana & Stanley Steyer Chair of Cancer Prevention and Control.   


Prof. Cohen founded the Tiberio Swartz Forum on Epidemiology of Infectious Diseases and Biosecurity, a very active national and international stage for scientific communications and discussions in the field of infectious diseases and vaccines. Additionally, he is the co-founder and co-director of the Summer International Institute of Advanced Epidemiology and Preventive Medicine at TAU School of Public Health. He also serves as an executive board member and the current Chairperson of the Middle East Consortium for Infectious Diseases Surveillance (MECIDS) and acts on various national and international advisory boards in the field of infectious diseases and vaccines. Prof. Cohen has been a consultant for the World Health Organization (WHO) on several occasions. In November 2020 Prof. Cohen was appointed to the COVID-19 solidarity vaccines trial candidate vaccine prioritization WHO working group.


Prof. Cohen has supervised many graduate and post-graduate students. He has received several awards for his outstanding contribution to research and is the author of more than 230 original, peer-reviewed articles.


Click here to view Prof. Cohen's CV (Short Version).​


Research Interests

  • Epidemiology of infectious diseases
  • Vaccinology
  • Development and evaluation of enteric vaccines
  • Risk and protective host factors associated with enteric diseases and in particular: shigellosis
  • Study of the association between selected infectious agents (e.g. Helicobacter pylori, Human Papilloma Virus) and cancer 


Selected Publications

Click here for a complete list of Prof. Cohen's Peer-Reviewed Articles. 


Publications (from the last three years)

Bassal R, Schejter E, Bachar R, Perri T, Korach J, Jakobson-Setton A, Ben-David LH, Cohen D, Keinan-Boker L. Risk Factors for Cervical Cancer and CIN3 in Jewish Women in Israel - Two Case Control Studies. Asian Pac J Cancer Prev. 2016;17(4):2067-73. 

Bassal R, Lerner L, Valinsky L, Agmon V, Peled N, Block C, Keller N, Keness Y, Taran D, Shainberg B, Ken-Dror S, Treygerman O, Rouach T, Lowenthal S, Shohat T, Cohen D. Trends in the Epidemiology of Campylobacteriosis in Israel (1999-2012). Foodborne Pathog Dis. 2016;13(8):448-55. 

Baker KS, Dallman TJ, Behar A, Weill FX, Gouali M, Sobel J, Fookes M, Valinsky L, Gal-Mor O, Connor TR, Nissan I, Bertrand S, Parkhill J, Jenkins C, Cohen D, Thomson NR. Travel- and Community-Based Transmission of Multidrug-Resistant Shigella sonnei Lineage among International Orthodox Jewish Communities. Emerg Infect Dis. 2016;22(9):1545-53. 

Glatman-Freedman A, Kaufman Z, Kopel E, Bassal R, Taran D, Valinsky L, Agmon V, Shpriz M, Cohen D, Anis E, Shohat T. Near real-time space-time cluster analysis for detection of enteric disease outbreaks in a community setting. J Infect. 2016;73(2):99-106.  

Muhsen K,Kassem E,Rubenstein U,Goren S,Ephros M, Cohen D,  Shulman LM. Incidence of rotavirus gastroenteritis hospitalizations and genotypes, before and five years after introducing universal immunization in Israel. Vaccine. 2016; 34(48):5916-5922. 

Miller-Roll T, Na'amnih W, Cohen D, Carmeli Y, Adler A. Molecular types and antimicrobial susceptibility patterns of Clostridium difficile isolates in different epidemiological settings in a tertiary care center in Israel. Diagn Microbiol Infect Dis. 2016; 86(4):450-454. 

Bassal R, Weil M, Cohen D, Mendelson E, Shohat T. Seroprevalence of Hepatitis A 12-years following the implementation of toddlers' vaccination: A population based study in Israel. Pediatric Infectious Diseases Journal. 2017; 36(10):e248-51. 

Na'amnih W, Adler A,  Miller-Roll T, Cohen D, Carmeli Y. Incidence and Risk Factors for Community and Hospital acquisition of Clostridium Difficile Infection in Tel Aviv Sourasky Medical Center. Infection Control & Hospital Epidemiology. 2017; 38(8):1-8 

Launay O, Lewis DJM, Anemona A, Loulergue P, Leahy J, Sciré AS, Maugard A, Marchetti E, Zancan S, Huo Z, Rondini S, Marhaba R, Finco O, Martin LB, Auerbach J, Cohen D, Saul A, Gerke C, Podda A. Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe. EBioMedicine. 2017 22:164-172. 

Bassal R, Shohat T, Kaufman Z, Mannasse B, Shinar E, Amichay D, Barak M, Ben-Dor A, Bar Haim A, Cohen D, Mendelson E, Lustig Y. The seroprevalence of West Nile Virus in Israel: A nationwide cross sectional study. PLoS One. 2017;12(6):e0179774.  

Bassal R, Markovich MP, Weil M, Shinar E, Carmeli Y, Dan M, Sofer D, Mendelson E, Cohen D, Shohat T. Prevalence of anti-hepatitis B surface antibodies among children and adolescents vaccinated in infancy and effect of booster dose administered within a pilot study. Epidemiol Infect. 2017;145(14):1-6 3.  

Lustig Y, Kaufman Z, Mendelson E, Orshan L, Anis E, Glazer Y, Cohen D, Shohat T, Bassal R. Spatial distribution of West Nile virus (WNV) in humans and mosquitoes in Israel, 2000-2014. Int J Infect Dis. 2017;64:20-6.  

Muhsen K, Anis E, Rubinstein U, Kassem E, Goren S, Shulman L, Ephros M, Cohen D. Effectiveness of rotavirus pentavalent vaccine under a universal immunization program in Israel, 2011-2015: a case-control study. Clinical Microbiology and Infection. 2018 (24)1:53-9 

Cohen NA, Miller T, Na’aminh W, Hod K, Adler A, Cohen D, Guzner-Gur H, Santo E, Halpern Z, Carmeli Y, Maharshak N. Clostridium difficile fecal toxin level is associated with disease severity and prognosis. United European Gastroenterol J. 2018;6(5):773-780. 

Sharabi S, Bassal R, Friedman N, Drori Y, Alter A, Glatman-Freedman A, Hindiyeh M, Cohen D, Mendelson E, Shohat T, Mandelboim M. Forty five percent of the Israeli population was infected with the influenza B Victoria virus during the winter season 2015-16. Oncotarget 2018;9(5):6623-6629. 

Na'amnih W, Adler A, Miller-Roll T, Cohen D, Carmeli Y. Risk factors for recurrent Clostridium difficile infection in a tertiary hospital in Israel. Eur J Clin Microbiol Infect Dis. 2018;37(7):1281-1288. 

Behar A, Baker KS, Bassal R, Ezernitchi A, Valinsky L, Thomson NR, Cohen D. Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel. Emerg Infect Dis. 2018;24(7):1335-1339. 

Rouach V, Goldshtein I, Wolf I, Catane R, Chodick G, Iton A, Stern N, Cohen D. Exposure to alendronate is associated with a lower risk of bone metastases in osteoporotic women with early breast cancer. J Bone Oncol. 2018;12:91-95. 

Muhsen K, Sinnreich R, Beer-Davidson G, Nassar H, Cohen D, Kark JD. Sero-prevalence of Helicobacter pylori CagA immunoglobulin G antibody, serum pepsinogens and haemoglobin levels in adults. Scientific reports. 2018;8(1):17616. 

Ciancarella V, Lembo-Fazio L, Paciello I, Bruno AK, Jaillon S, Berardi S, Barbagallo M, Meron-Sudai S, Cohen D, Molinaro A, Rossi G. Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection. PLoS pathogens. 2018;14(12):e1007469. 

Rouach V, Goldshtein I, Buch A, Catane R, Chodick G, Stern N, Shalev V, Cohen D. The association between adherence with oral bisphosphonates and the risk of breast cancer in post-menopausal women. Journal of Bone Oncology. 2018; 12:91-95 

Bercovich S, Anis E, Kassem E, Rubinstein U, Ephros M, Cohen D, Muhsen K. Validation of parental reports of rotavirus vaccination of their children compared to the national immunization registry. Vaccine 2019;37:2791-2796. 

Muhsen K, Sinnreich R, Merom D, Beer-Davidson G, Nassar H, Cohen D, Kark JD. Prevalence and determinants of serological evidence of atrophic gastritis among Arab and Jewish residents of Jerusalem: a cross-sectional study. BMJ open. 2019;9(1):e024689. 

Katz D, Ben-Chetrit E, Sherer SS, Cohen D, Muhsen K. Correlates of non-typhoidal Salmonella bacteraemia: a case-control study. International Journal of Infectious Diseases. 2019; 81:170-175. 

Kaminski RW, Pasetti MF, Aguilar AO, Clarkson KA, Rijpkema S, Bourgeois AL, Cohen D, Feavers I, MacLennan CA. Consensus Report on Shigella Controlled Human Infection Model: Immunological Assays. Clinical Infectious Diseases. 2019;69(Supplement_8):S596-601. 

Cohen D, Korin H, Bassal R, Perry Markovich M, Sivan Y, Goren S, Muhsen K. Burden and risk factors of Shigella sonnei shigellosis among children aged 0-59 months in hyperendemic communities in Israel. Int J Infect Dis 2019; 82:117-123. 

Cohen D, Meron-Sudai S, Bialik A, Asato V, Goren S, Ariel-Cohen O, Reizis A, Hochberg A, Ashkenazi S. Serum IgG antibodies to Shigella lipopolysaccharide antigens - a correlate of protection against shigellosis. Hum Vaccin Immunother 2019; 15:1401-1408. 

Cohen D, Muhsen K. Vaccines for enteric diseases. Hum Vaccin Immunother 2019; 15:1205-1214. 

Koren R, Bassal R, Shohat T, Cohen D, Mor O, Mendelson E, Lustig Y. Presence of Antibodies against Sindbis Virus in the Israeli Population: A Nationwide Cross-Sectional Study. Viruses 2019;11. 

Mani S, Toapanta FR, McArthur MA, Qadri F, Svennerholm AM, Devriendt B, Phalipon A, Cohen D, Sztein MB. Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development. Vaccine. 2019; 37(34), 4787-4793. 

Muhsen K, Kassem E, Rubenstein U, Goren S, Ephros M, Shulman LM, Cohen D. No evidence of an increase in the incidence of norovirus gastroenteritis hospitalizations in young children after the introduction of universal rotavirus immunization in Israel. Hum Vaccin Immunother 2019;15:1284-1293. 

Muhsen K, Sinnreich R, Merom D, Nassar H, Cohen D, Kark JD. Helicobacter pylori infection, serum pepsinogens as markers of atrophic gastritis, and leukocyte telomere length: a population-based study. Hum Genomics 2019;13:32. 

Sagie S, Na'amnih W, Frej J, Cohen D, Alpert G, Muhsen K. Correlates of hospitalizations in internal medicine divisions among Israeli adults of different ethnic groups with hypertension, diabetes and cardiovascular diseases. PLoS One 2019; 14(4) 

Falup-Pecurariu O, Lixandru RI, Cojocaru E, Csutak K, Monescu V, Muhsen K, Falup-Pecurariu C, Cohen D. Shiga toxin producing Escherichia coli-associated diarrhea and hemolytic uremic syndrome in young children in Romania. Gut pathogens. 2019; 11(1):46. 

Muhsen K, Na'amnih W, Adler A, Carmeli Y, Cohen D. Clostridium difficile‐associated disease and Helicobacter pylori seroprevalence: A case‐control study. Helicobacter. 2020; 25(1):e12668.

Bassal R, Indenbaum V, Pando R, Levin T, Shinar E, Amichay D, Barak M, Ben-Dor A, Haim AB, Mendelson E, Cohen D, Shohat T. Seropositivity of measles antibodies in the Israeli population prior to the nationwide 2018 - 2019 outbreak. Hum Vaccin Immunother. 2020 Oct 29:1-5. 2.

Maor Y, Cohen D, Paran N, Israely T, Ezra V, Axelrod O, Shinar E, Izak M, Rahav G, Rahimi-Levene N, Bazofin BM, Gelman R, Dicker D, Brosh-Nissimov T, Megged O, Dahan D, Benov A, Paz A, Edward K, Moran A, Rogowski O, Sorkine P, Mayo A, Zimhony O, Chen J. Compassionate use of convalescent plasma for treatment of moderate and severe pneumonia in COVID-19 patients and association with IgG antibody levels in donated plasma. EClinicalMedicine. 2020 Sep;26 3.

Cohen D, Atsmon J, Artaud C, Meron-Sudai S, Gougeon M-L, Bialik A, Goren S, Asato V, Ariel-Cohen O, Reizis A, Dorman A, Hoitink CWG, Westdijk J, Ashkenazi S, Sansonetti P, Mulard LA, Phalipon A.  Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose escalating, single-blind, randomised, placebo-controlled study. Lancet Inf Dis. (In press)

Clinical Study Protocols

"A Phase I Dose Escalation Study to Assess the Safety and Immunogenicity of the SF2a-TT15 Conjugate Vaccine against S. flexneri 2a in Healthy Adult Volunteers." 2015. Click here to view. 

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