Publications (last 5 years)
65. Pode-Shakked N, Harari-Steinberg O, Haberman-Ziv Y, Rom-Gross E, Bahar S, Omer D, Metsuyanim S, Buzhor E, Goldstein RS, Mark-Danieli M, Dekel B. Featured article: Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target. Oncogene 2011;30(14):1664-80. B1
Highlighted in Global Medical Discovery:
http://globalmedicaldiscovery.com/key-scientific-articles/resistance-or-sensitivity-of-wilms-tumor-to-anti-fzd7-antibody-highlights-the-wnt-pathway-as-a-possible-therapeutic-target/
66. Pode-Shakked N, Dekel B, Wilms' tumor – a renal stem cell malignancy? Pediatr Nephrol. 2011 Sep;26(9):1535-43
67. Harari-Steinberg O, Pleniceanu O, Dekel B. Selecting the optimal cell for kidney regeneration: fetal, adult or reprogrammed stem cells. Organogenesis 2011 Apr 1;7(2).
68. Buzhor E, Harari-Steinberg O, Omer D, Mark-Danieli M, Noiman T, Goldstein RS, Dekel B. Kidney spheroids recapitulate tubular organoids leading to enhanced tubulogenic potency of human kidney-derived cells. Tissue Eng 2011;17(17-18):2305-19. B1
69. Noiman T*, Buzhor E*, Zangi L, Harari-Steinberg O, Dekel B, Goldstein RS. A rapid, economical and humane in-vivo assay system for analyzing organogenetic capacity of human kidney cells. Organogenesis 2011 Apr 1;7(2). * Equal first authors B1
70. Vivante A*,Lotan D*,Pode-Shakked N*, Landau D , Svec P, Nampoothiri S, Verma I, Abu-Libdeh A, Bockenhauer D, Dekel B**, and Anikster Y**. Familial Autosomal Recessive Renal Tubular Acidosis: Importance of Early Diagnosis. Nephron Physiol 2011;119(3):p31-p39.. ** Equal senior authors, corresponding author (Dekel B) B1
71. Machol K, Vivante A, Rubinsthein N, Dekel B, Paret G. Keeping the Heart in Mind when Managing Hemolytic Uremic Syndrome. Isr Med Assoc J. 2011;13(7):446-7. CASE REPORT
72. Kovalski Y, Cleper R, Krause I, Dekel B, Belenky A, Davidovits M. Hyponatremic hypertensive syndrome in pediatric patients: is it really so rare? Pediatr Nephrol. 2012 Jun;27(6):1037-40. B1
73. Has C, Spartà G, Kiritsi D, Weibel L, Moeller A, Vega-Warner V, Waters A, He Y, Anikster Y, Esser P, Straub BK, Hausser I, Bockenhauer D, Dekel B, Hildebrandt F, Bruckner-Tuderman L, Laube GF. Integrin α3 mutations with kidney, lung, and skin disease. N Engl J Med. 2012;366(16):1508-14. B1
74. Bussolati B, Dekel B, Azzarone B, Camussi G. Human renal cancer stem cells. Cancer Lett. 2013;338(1):141-6. REVIEW
75. Pode-Shakked N, Shukron R, Bahar S, Pri-Chen S, Tsvetkov P, Goldstein RS, Rom-Gross E, Mor Y, Fridman E, Goldmacher VS, Harari-Steinberg O, Mark-Danieli M, Dekel B. Isolation and characterization of renal cancer initiating cells in wilms tumor xenografts unveils new therapuetic targets. EMBO Mol Med, 2013;5(1):18-37. B1
Accompanying Focus Article: The Stem and Roots of Wilms Tumor, http://dx.doi.org/10.1002/emmm.201202173.
EMBO press release: http://www.embo.org/news-a-media-centre/press-releases/cancer-stem-cells-isolated-from-kidney-tumours.html
76. Vivante A, Mark-Danieli M, Davidovits M, Harari-Steinberg O, Omer D, Gnatek Y, Cleper R, Landau D, Kovalski Y, Weissman I, Eisenstein I, Soudack M, Wolf HR, Issler N, Lotan D, Anikster Y, Dekel B. Renal hypodysplasia associates with a WNT4 variant that causes aberrant canonical WNT signaling. J Am Soc Nephrol. 2013;24(4):550-8. B1
Highlighted in Global Medical Discovery
77. Pleancianu O, Dekel B. Book chapter: Stem Cells in Fetal Tissue (The Kidney as a Model) in Human Fetal Tissue Transplantation, Bhattacharya Ed. Springer-Verlag London 2013. BOOK CHAPTER
78. Omer D, Harari-Steinberg O, Pleaniceanu O, Buzhor E, Metsuyanim S, Goldstein RS, Dekel B. Featured article: Chromatin-modifying agents reactivate embryonic renal stem/progenitor genes in human adult kidney epithelial cells but abrogate dedifferentiation and stemness. Omer D, Harari-Steinberg O, Buzhor E, Metsuyanim S, Pleniceanu O, Zundelevich A, Gal-Yam EN, Dekel B. Cell Reprogram. 2013;15(4):281-92. B1
79. Shukrun R, Pode Shakked N, Dekel B. Targeted therapy aimed at cancer stem cells: Wilms' tumor as an example. Pediatr Nephrol. 2013 Jun 13. [Epub ahead of print] REVIEW
80. Harari-Steinberg O* Metsuyanim S*, Omer D, Gnatek Y, Gershon R, Pri-Chen S, Ozdemir DD, Lerenthal Y, Noiman T, Ben-Hur H, Vaknin Z, Schenider DF, Aronow BJ, Goldstein RS, Buzhor E, Hohenstein P, Dekel B. Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease. EMBO Mol Med 2013;5(10):1556-68. B1
81. Buzhor E, Omer D, Harari-Steinberg O, Vax E, Metsuyanim S, Noiman T, Goldstein RS, Dekel B. Re-activation of NCAM1 defines a sub-population of human adult kidney epithelial cells with clonogenic and stem/progenitor properties. Am J Pathol 2013;183(5):1621-33. B1
82. Pode B, Bunjanover Y, Dekel B, Anikster Y. The bitterness of Glucose/Galactose: Novel mutations in the SLC5A1 gene. J Pediatr Gastroenterol Nutr 2014;58(1):57-60. B1
83. Shukrun R, Vivante A, Pleniceanu O, Vax E, Anikster Y, Dekel B**, Lotan D**. A human integrin-α3 mutation confers major renal developmental defects. PLoS One. 2014 12;9(3):e90879. **Equal senior authors, corresponding author (Dekel B) B1
84. Rinkevich Y, Montoro DT, Contreras-Trujillo H, Harari-Steinberg O, Newman AM, Lim X, Van-Amerongen R, Bowman A,. Tsai JM, Nusse R, Longaker MT, *Weissman IL, *Dekel B. In vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance and Regeneration. Cell Reports, 2014;7(4):1270-83 (*equal last authors). B1
85. Urbach A, Yermalovich A, Zhang J, Spina CS, Zhu H, Perez-Atayde AR, Shukrun R, Charlton J, Sebire N, Mifsud W, Dekel B, Pritchard-Jones K, Daley GQ. Lin28 sustains early renal progenitors and induces Wilms tumor. Genes and Development, 2014;28(9):971-82. B1
86. Shukrun R; Pode-Shakked N; Pleniceanu O, Omer D, Vax E, Pri-Chen S, Hu Q, Harari-Steinberg O, Huff V, Dekel B. Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk. Stem Cell Reports. 2014;3(1):24-33. B1
87. Dziedzic K, Pleniceanu O, Dekel B. Kidney stem cells in development, regeneration and cancer. (Invited Review). Semin Cell Dev Biol. Semin Cell Dev Biol. 2014;36:57-65 REVIEW
88. Schlingmann KP, Ruminska J, Kaufmann M, Dursun I, Patti M, Kranz B, Pronicka E, Ciara E, Akcay T, Bulus D, Cornelissen EA, Gawlik A, Sikora P, Patzer L, Galiano M, Boyadzhiev V, Dumic M, Vivante A, Kleta R, Dekel B, Levtchenko E, Bindels RJ, Rust S, Forster IC, Hernando N, Jones G, Wagner CA, Konrad M. Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia.
J Am Soc Nephrol. 2015 Jun 5. pii: ASN.2014101025. [Epub ahead of print]
89. Romagnani P, Rinkevich Y, Dekel B. Current lineage tracing methods to study kidney regeneration, their limitations and advantages. Nat Rev Nephrol. 2015;11(7):420-31REVIEW
90. Pleancianu O, Dekel B. Book chapter: Renal Stem Cells in Oxford Textbook of Clinical Nephrology (4th edition, Chief Ed. Neil Turner). Oxford University Press 2015.
91. Pleancianu O, Dziedzic K, Dekel B. From embryonic rudiments to renal stem/progenitor cells in Kidney Development, Disease, Repair and Regeneration, 1st Edition (Ed. Little MH). Elsevier 2015.
92. Sanyal M, Morimoto M, Baradaran-Heravi A, Choi K, Kambham N, Jensen K, Dutt S, Dionis-Petersen KY, Liu LX, Felix K, Mayfield C, Dekel B, Bokenkamp A, Fryssira H, Guillen-Navarro E, Lama G, Brugnara M, Lücke T, Olney AH, Hunley TE, Polat AI, Yis U, Bogdanovic R, Mitrovic K, Berry S, Najera L, Najafian B, Gentile M, Nur Semerci C, Tsimaratos M, Lewis DB, Boerkoel CF. Lack of IL7Rα expression in T cells is a hallmark of T-cell immunodeficiency in Schimke immuno-osseous dysplasia (SIOD). Clin Immunol. 2015 Oct 21;161(2):355-365. doi: 10.1016/j.clim.2015.10.005. [Epub ahead of print]
93. Dekel B. The ever expanding kidney repair shop (Invited Editorial). J Am Soc Nephrol. 2015 Dec 7. pii: ASN.2015111207. [Epub ahead of print]
94. Pode-Shakked N, Pleniceanu O, Gershon R, Shukrun R, Kanter I, Bucris E, Pode-Shakked B, Tam G, Tam H, Caspi R, Pri-Chen S, Vax E, Katz G, Omer D, Harari-Steinberg O, Kalisky T, Dekel B. Dissecting Stages of Human Kidney Development and Tumorigenesis with Surface Markers Affords Simple Prospective Purification of Nephron Stem Cells. Sci Rep. 2016;6:23562.
95. Gilboa Y, Perlman S, Pode-Shakked N, Pode-Shakked B, Shrim A, Azaria-Lahav E, Dekel B, Yonath H, Berkenstadt M, Achiron R.Prenatal diagnosis of 17q12 deletion syndrome: from fetal hyperechogenic kidneys to high risk for autism. Prenat Diagn. 2016 Nov;36(11):1027-1032.
96. Perlman S, Lotan D, Dekel B, Kivilevitch Z, Hazan Y, Achiron R, Gilboa Y. Prenatal compensatory renal growth in unilateral renal agenesis. Prenat Diagn. 2016;36(11):1075-1080.
97. Pleniceanu O, Shukrun R, Omer D, Vax E, Kanter I, Dziedzic K, Pode-Shakked N, Mark-Daniei M, Pri-Chen S, Gnatek Y, Alfandary H, Varda-Bloom N, Bar-Lev DD, Bollag N, Shtainfeld R, Armon L, Urbach A, Kalisky T, Nagler A, Harari-Steinberg O, Arbiser JL, Dekel B. PPARg is central to initiation and propagation of human angiomyolipoma suggesting its potential as a therapeutic target. EMBO Mol Med. 2017 Apr;9(4):508-530.
98. Vivante A, Mann N, Yonath H,‡ Weiss AC, Getwan M,| Kaminski M, Bohnenpoll T, Teyssier C, Chen J, Shril S, van der Ven AT, Ityel H, Schmidt JM, Widmeier E, Bauer SB, Sanna-Cherchi S, Gharavi AG, Lu W, Magen D, Shukrun R, Lifton R Tasic V, Stanescu HC, Cavaillès V, Robert Kleta, Anikster Y, Dekel B, Kispert A, Lienkamp SS, Hildebrandt H.
A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling
J Am Soc Nephrol 2017 Apr 5. pii: ASN.2016060694. doi: 10.1681/ASN.2016060694.
99. Pillar N, Pleniceanu O, Fang M, Ziv L, Botchan S, Cheng L, Dekel B*, Shomron N* A novel variant in the FHL1 gene associated with X-linked recessive hypoparathyroidism. Hum Genetics 2017 Jul;136(7):835-845. (*equal last and corresponding authors.).
100. Zajicek M, Perlman S, Dekel B, Lahav E, Lotan D, Lotan D, Achiron R, Gilboa Y.
Crossed ectopic kidney: prenatal diagnosis and postnatal follow-up.
Prenat Diagn. 2017 May 15. doi: 10.1002/pd.5070.
101. Pode-Shakked N, Gershon R, Tam G, Omer D, Gnatek Y, Kanter I, Oriel S, Katz G, Harari-Steinberg O, Kalisky T, Dekel B. Evidence for in vitro preservation of human nephrogeneis at the single cell level. Stem Cell Reports 2017 May 25. pii: S2213-6711(17)30180-7.
102. Markovsky E, Vax E, Ben-Shushan D, Eldar-Boock A, Shukrun R , Yeini E, Barshack I, Caspi R, Harari-Steinberg O, Pode-Shakked N, Dekel B*, Satchi-Fainaro R*. Wilms tumor NCAM-expressing cancer stem cells as potential therapeutic target for polymeric nanomedicine
Mol Cancer Ther. 2017 Jul 20. doi: 10.1158/1535-7163.MCT-17-0184. [Epub ahead of print]
(*equal last and corresponding authors.).
103. Pleniceanu O, Omer D, Azaria E, Dekel B. mTOR inhibition for sporadic angiomyolipoma. Kidney Int Reports (in press)
104. Golan H, Shukrun R, Mark-Daniely M, Pode-Shakked N; Pleniceanu O, Omer D, Vax E, Pri-Chen S, Harari-Steinberg O, Toren A, Dekel B. Long term in vivo propagation of human malignant rhabdoid tumor as a platform to identify and target CIC/CSCs . (Under revision).
105. Omer D, Harari-Steinberg O, Buzhor E, Metsuyanim S, Gal-Yam, Dekel B. Reprogramming human adult kidney epithelia into long-term self-renewing proximal tubule progenitors via ectopic Oct4 expression. (Submitted).