פרופ' רחל [חלי] דנקנר

אפידמיולוגית ראשית - מכון גרטנר לחקר אפידמיולוגיה ומדיניות בריאות, מרכז רפואי ע"ש ח. שיבא, תל השומר

פרופסור מן המניין, מסלול רגיל – החוג לאפידמיולוגיה ורפואה מונעת, בית הספר לבריאות הציבור, הפקולטה לרפואה ע"ש סאקלר, אוניברסיטת תל אביב

מנהלת - מכון מחקר ופיתוח, ביה"ח השיקומי "רעות תל אביב"

חוקרת עמיתה - Patient Oriented Research, The Feinstein Institute for Medical Research Manhasset, North Shore, New York 11030, USA

1991 – תואר M.D., ביה"ס לרפואה, האוניברסיטה העברית בירושלים.

1995 – תואר M.P.H., ביה"ס לבריאות הציבור ע"ש ג'והנס הופקינס, בולטימור, מרילנד, ארה"ב.

1998 – מומחית בבריאות הציבור, רפואה.

1999 – דיפלומה ברפואת ספורט, לימודי המשך בביה"ס לרפואה ע"ש סאקלר, אוניברסיטת תל אביב.

2001 – הסמכה ברפואת צלילה, חיל הים הישראלי.

2001, 2002 – הסמכה לרופאי נבחרות ספורט, American College of Sports Medicine (ACSM)

2007-2009 – קלינאית חוקרת בפיתוח תרופות לסוכרת, חברת פייזר, קונטיקט, ארה"ב

2010, 2018, 2019 – הסמכה ל-GCP (Good Clinical Practice)

רשימת הפרסומים המלאה של פרופ' דנקנר זמינה באתרים הבאים :  Pubmed / Google Scholar / Web Of Science

רשימת פרסומים נבחרים מ - 5 השנים האחרוניות:

1. Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK, Song RJ, Burgess S, Posner DC, Mosconi K, Robinson-Cohen C, Mason A, Bolton TR, Tao R, Allara E, Schubert P, Chen L, Staley JR, Staplin N, Altay S, Amiano P, Arndt V, Ärnlöv J, Barr ELM, Björkelund C, Boer JMA, Brenner H, Casiglia E, Chiodini P, Cooper JA, Coresh J, Cushman M, Dankner R, Davidson KW, de Jongh RT, Donfrancesco C, Engström G, Freisling H, de la Cámara AG, Gudnason V, Hankey GJ, Hansson PO, Heath AK, Hoorn EJ, Imano H, Jassal SK, Kaaks R, Katzke V, Kauhanen J, Kiechl S, Koenig W, Kronmal RA, Kyrø C, Lawlor DA, Ljungberg B, MacDonald C, Masala G, Meisinger C, Melander O, Moreno Iribas C, Ninomiya T, Nitsch D, Nordestgaard BG, Onland-Moret C, Palmieri L, Petrova D, Garcia JRQ, Rosengren A, Sacerdote C, Sakurai M, Santiuste C, Schulze MB, Sieri S, Sundström J, Tikhonoff V, Tjønneland A, Tong T, Tumino R, Tzoulaki I, van der Schouw YT, Monique Verschuren WM, Völzke H, Wallace RB, Goya Wannamethee S, Weiderpass E, Willeit P, Woodward M, Yamagishi K, Zamora-Ros R, Akwo EA, Pyarajan S, Gagnon DR, Tsao PS, Muralidhar S, Edwards TL, Damrauer SM, Joseph J, Pennells L, Wilson PWF, Harrison S, Gaziano TA, Inouye M; Million Veteran Program, Baigent C, Casas JP, Langenberg C, Wareham N, Riboli E, Michael Gaziano J, Danesh J, Hung AM, Butterworth AS, Wood AM, Di Angelantonio E; Emerging Risk Factors Collaboration/EPIC-CVD/Million Veteran Program. Circulation. 2022 Oct 31. doi: 10.1161/CIRCULATIONAHA.122.060700. Online ahead of print. PMID: 36314129
2. High variation between healthcare professionals in nutrition therapy plans of patients with feeding tubes admitted to a long-term rehabilitation center from an acute-care hospital. Marom P, Rayyan-Assi H, Stein-Reisner O, Brik M, Gershoni-Kait M, Bornstein L, Zalcman BG, Albukrek D, Dankner R. Nutr Clin Pract. 2022 Sep 25. doi: 10.1002/ncp.10910. Online ahead of print. PMID: 36161357.
3. The insulin sensitivity Mcauley index (MCAi) is associated with 40-year cancer mortality in a cohort of men and women free of diabetes at baseline.  Moshkovits Y, Rott D, Chetrit A, Dankner R. PLoS One. 2022 Aug 3;17(8):e0272437. doi: 10.1371/journal.pone.0272437. eCollection 2022. PMID: 35921366
4. [PREDICTION MODEL FOR ASSESSING PHYSICAL FITNESS IN CARDIAC PATIENTS]. Bagizada S, Chetrit A, Dankner R. Harefuah. 2022 Jul;161(7):419-425. PMID: 35833427 Hebrew.  
5. Association between Self-Classification of COVID-19 Risk Levels and Adverse Lifestyle Changes among Physically Active Older Adults Following the Coronavirus Outbreak. Marom P, Zalcman BG, Dankner R. Int J Environ Res Public Health. 2022 Jun 8;19(12):7039. doi: 10.3390/ijerph19127039. PMID: 35742285
6. Is health-related quality of life 1-year after coronary artery bypass graft surgery associated with living in a greener environment? Sadeh M, Agay N, Brauer M, Chudnovsky A, Ziv A, Dankner R. Environ Res. 2022 Sep;212(Pt C):113364. doi: 10.1016/j.envres.2022.113364. Epub 2022 Apr 26. PMID: 35487257
7. Hyperglycaemic disorders associated with PCSK9 inhibitors: a real-world, pharmacovigilance study. Goldman A, Raschi E, Cukierman-Yaffe T, Dankner R, Shouval R, Shechter M, Ben-Zvi I, Gerstein HC, Maor E. Eur J Prev Cardiol. 2022 Jul 20;29(9):1334-1342. doi: 10.1093/eurjpc/zwab209. PMID: 34897409
8. Metformin Treatment Among Men With Diabetes and the Risk of Prostate Cancer: A Population-Based Historical Cohort Study. Freedman LS, Agay N, Farmer R, Murad H, Olmer L, Dankner R. Am J Epidemiol. 2022 Mar 24;191(4):626-635. doi: 10.1093/aje/kwab287. PMID: 34893792
9. Residential greenness and increased physical activity in patients after coronary artery bypass graft surgery. Sadeh M, Brauer M, Chudnovsky A, Ziv A, Dankner R. Eur J Prev Cardiol. 2021 Sep 20;28(11):1184-1191. doi: 10.1177/2047487319886017. Epub 2019 Dec 3. PMID: 34551086  
10. Cardiovascular Toxicities of Antiangiogenic Tyrosine Kinase Inhibitors: A Retrospective, Pharmacovigilance Study. Goldman A, Bomze D, Dankner R, Fourey D, Boursi B, Arad M, Maor E. Target Oncol. 2021 Jul;16(4):471-483. doi: 10.1007/s11523-021-00817-2. Epub 2021 May 10. PMID: 33970401
11. The association between insulin sensitivity indices, ECG findings and mortality: a 40-year cohort study. Moshkovits Y, Rott D, Chetrit A, Dankner R. Cardiovasc Diabetol. 2021 May 6;20(1):97. doi: 10.1186/s12933-021-01284-9. PMID: 33957929
12. Erratum. Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Diabetes Care 2021;44:1062-1069.  Ahuja V, Aronen P, Pramodkumar TA, Looker H, Chetrit A, Bloigu AH, Juutilainen A, Bianchi C, La Sala L, Anjana RM, Pradeepa R, Venkatesan U, Jebarani S, Baskar V, Fiorentino TV, Timpel P, DeFronzo RA, Ceriello A, Del Prato S, Abdul-Ghani M, Keinänen-Kiukaanniemi S, Dankner R, Bennett PH, Knowler WC, Schwarz P, Sesti G, Oka R, Mohan V, Groop L, Tuomilehto J, Ripatti S, Bergman M, Tuomi T. Diabetes Care. 2021, Jun;44(6):1457. doi: 10.2337/dc21-er06c. Epub 2021 Apr 30. PMID: 33931489 Free PMC article. No abstract available.
13. Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Ahuja V, Aronen P, Pramodkumar TA, Looker H, Chetrit A, Bloigu AH, Juutilainen A, Bianchi C, La Sala L, Anjana RM, Pradeepa R, Venkatesan U, Jebarani S, Baskar V, Fiorentino TV, Timpel P, DeFronzo RA, Ceriello A, Del Prato S, Abdul-Ghani M, Keinänen-Kiukaanniemi S, Dankner R, Bennett PH, Knowler WC, Schwarz P, Sesti G, Oka R, Mohan V, Groop L, Tuomilehto J, Ripatti S, Bergman M, Tuomi T. Diabetes Care. 2021 Apr;44(4):1062-1069. doi: 10.2337/dc20-1688. PMID: 33741697 Free PMC article. Review.
14. Years of potential life lost in pre-diabetes and diabetes mellitus: data from a 40-year follow-up of the Israel study on Glucose intolerance, Obesity and Hypertension. Rapoport M, Chetrit A, Cantrell D, Novikov I, Roth J, Dankner R. BMJ Open Diabetes Res Care. 2021 Mar;9(1):e001981. doi: 10.1136/bmjdrc-2020-001981. PMID: 33692115
15. High Expression Level of PPARγ in CD24 Knockout Mice and Gender-Specific Metabolic Changes: A Model of Insulin-Sensitive Obesity. Shapira S, Kazanov D, Dankner R, Fishman S, Stern N, Arber N. J Pers Med. 2021 Jan 15;11(1):50. doi: 10.3390/jpm11010050. PMID: 33467499
16. Remote sensing metrics to assess exposure to residential greenness in epidemiological studies: A population case study from the Eastern Mediterranean. Sadeh M, Brauer M, Dankner R, Fulman N, Chudnovsky A. Environ Int. 2021 Jan;146:106270. doi: 10.1016/j.envint.2020.106270. Epub 2020 Dec 2. PMID: 33276312
17. Cardiovascular adverse events associated with hydroxychloroquine and chloroquine: A comprehensive pharmacovigilance analysis of pre-COVID-19 reports. Goldman A, Bomze D, Dankner R, Hod H, Meirson T, Boursi B, Maor E. Br J Clin Pharmacol. 2021 Mar;87(3):1432-1442. doi: 10.1111/bcp.14546. Epub 2020 Sep 22. PMID: 32964535
18. More recent, better designed studies have weakened links between antidiabetes medications and cancer risk. Dankner R, Roth J. Diabet Med. 2020 Feb;37(2):194-202. doi: 10.1111/dme.14179. Epub 2020 Jan 3. PMID: 31769894 Review.
19. Imputing missing time-dependent covariate values for the discrete time Cox model. Murad H, Dankner R, Berlin A, Olmer L, Freedman LS. Stat Methods Med Res. 2020 Aug;29(8):2074-2086. doi: 10.1177/0962280219881168. Epub 2019 Nov 3. PMID: 31680633
20. Data for a population based cohort study on abnormal findings of electrocardiograms (ECG), recorded during follow-up periodic examinations, and their association with long-term cardiovascular morbidity and all-cause mortality. Goldman A, Hod H, Chetrit A, Dankner R. Data Brief. 2019 Sep 5;26:104474. doi: 10.1016/j.dib.2019.104474. eCollection 2019 Oct. PMID: 31667239
21. ApoE Genotype, Lipid Profile, Exercise, and the Associations With Cardiovascular Morbidity and 18-Year Mortality. Dankner R, Ben Avraham S, Harats D, Chetrit A. J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1887-1893. doi: 10.1093/gerona/glz232. PMID: 31585002
22. Incidental abnormal ECG findings and long-term cardiovascular morbidity and all-cause mortality: A population based prospective study. Goldman A, Hod H, Chetrit A, Dankner R. Int J Cardiol. 2019 Nov 15;295:36-41. doi: 10.1016/j.ijcard.2019.08.015. Epub 2019 Aug 7. PMID: 31412991
23. Metformin Treatment and Cancer Risk: Cox Regression Analysis, With Time-Dependent Covariates, of 320,000 Persons With Incident Diabetes Mellitus. Dankner R, Agay N, Olmer L, Murad H, Keinan Boker L, Balicer RD, Freedman LS. Am J Epidemiol. 2019 Oct 1;188(10):1794-1800. doi: 10.1093/aje/kwz157. PMID: 31269196
24. Cardiovascular Risk Factors Associated With Venous Thromboembolism. Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P, Burgess S, Bell S, Sweeting M, Rimm EB, Kabrhel C, Zöller B, Assmann G, Gudnason V, Folsom AR, Arndt V, Fletcher A, Norman PE, Nordestgaard BG, Kitamura A, Mahmoodi BK, Whincup PH, Knuiman M, Salomaa V, Meisinger C, Koenig W, Kavousi M, Völzke H, Cooper JA, Ninomiya T, Casiglia E, Rodriguez B, Ben-Shlomo Y, Després JP, Simons L, Barrett-Connor E, Björkelund C, Notdurfter M, Kromhout D, Price J, Sutherland SE, Sundström J, Kauhanen J, Gallacher J, Beulens JWJ, Dankner R, Cooper C, Giampaoli S, Deen JF, Gómez de la Cámara A, Kuller LH, Rosengren A, Svensson PJ, Nagel D, Crespo CJ, Brenner H, Albertorio-Diaz JR, Atkins R, Brunner EJ, Shipley M, Njølstad I, Lawlor DA, van der Schouw YT, Selmer RM, Trevisan M, Verschuren WMM, Greenland P, Wassertheil-Smoller S, Lowe GDO, Wood AM, Butterworth AS, Thompson SG, Danesh J, Di Angelantonio E, Meade T; Emerging Risk Factors Collaboration. JAMA Cardiol. 2019 Feb 1;4(2):163-173. doi: 10.1001/jamacardio.2018.4537. PMID: 30649175
25. The metabolic syndrome and its components are differentially associated with chronic diseases in a high-risk population of 350 000 adults: A cross-sectional study.  Rayyan Assi H, Ziv A, Dankner R. Diabetes Metab Res Rev. 2019 May;35(4):e3121. doi: 10.1002/dmrr.3121. Epub 2019 Jan 28. PMID: 30600581
26. Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies. Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, Burgess S, Willeit P, Bolton T, Moons KGM, van der Schouw YT, Selmer R, Khaw KT, Gudnason V, Assmann G, Amouyel P, Salomaa V, Kivimaki M, Nordestgaard BG, Blaha MJ, Kuller LH, Brenner H, Gillum RF, Meisinger C, Ford I, Knuiman MW, Rosengren A, Lawlor DA, Völzke H, Cooper C, Marín Ibañez A, Casiglia E, Kauhanen J, Cooper JA, Rodriguez B, Sundström J, Barrett-Connor E, Dankner R, Nietert PJ, Davidson KW, Wallace RB, Blazer DG, Björkelund C, Donfrancesco C, Krumholz HM, Nissinen A, Davis BR, Coady S, Whincup PH, Jørgensen T, Ducimetiere P, Trevisan M, Engström G, Crespo CJ, Meade TW, Visser M, Kromhout D, Kiechl S, Daimon M, Price JF, Gómez de la Cámara A, Wouter Jukema J, Lamarche B, Onat A, Simons LA, Kavousi M, Ben-Shlomo Y, Gallacher J, Dekker JM, Arima H, Shara N, Tipping RW, Roussel R, Brunner EJ, Koenig W, Sakurai M, Pavlovic J, Gansevoort RT, Nagel D, Goldbourt U, Barr ELM, Palmieri L, Njølstad I, Sato S, Monique Verschuren WM, Varghese CV, Graham I, Onuma O, Greenland P, Woodward M, Ezzati M, Psaty BM, Sattar N, Jackson R, Ridker PM, Cook NR, D'Agostino RB, Thompson SG, Danesh J, Di Angelantonio E; Emerging Risk Factors Collaboration. Eur Heart J. 2019 Feb 14;40(7):621-631. doi: 10.1093/eurheartj/ehy653. PMID: 30476079
27. A historical cohort study on glycemic-control and cancer-risk among patients with diabetes. Dankner R, Boker LK, Boffetta P, Balicer RD, Murad H, Berlin A, Olmer L, Agai N, Freedman LS. Cancer Epidemiol. 2018 Dec;57:104-109. doi: 10.1016/j.canep.2018.10.010. Epub 2018 Oct 28. PMID: 30388485
28. Is there evidence for sex differences in the association between diabetes and cancer? Dankner R, Boker LK, Freedman LS. Diabetologia. 2019 Jan;62(1):199-200. doi: 10.1007/s00125-018-4756-2. Epub 2018 Oct 27. PMID: 30368553 No abstract available.  
29. Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/L). Bergman M, Manco M, Sesti G, Dankner R, Pareek M, Jagannathan R, Chetrit A, Abdul-Ghani M, Buysschaert M, Olsen MH, Nilsson PM, Medina JL, Roth J, Groop L, Del Prato S, Raz I, Ceriello A. Diabetes Res Clin Pract. 2018 Dec;146:18-33. doi: 10.1016/j.diabres.2018.09.017. Epub 2018 Sep 28. PMID: 30273707 Review.
30. Reuniting overnutrition and undernutrition, macronutrients, and micronutrients. Kim M, Basharat A, Santosh R, Mehdi SF, Razvi Z, Yoo SK, Lowell B, Kumar A, Brima W, Danoff A, Dankner R, Bergman M, Pavlov VA, Yang H, Roth J. Diabetes Metab Res Rev. 2019 Jan;35(1):e3072. doi: 10.1002/dmrr.3072. Epub 2018 Oct 4. PMID: 30171821 Review.
31. Associations of dietitian follow-up counselling visits and physical exercise with weight loss one year after sleeve gastrectomy. Kessler Y, Olmer L, Raziel A, Goitein D, Dankner R. Eat Weight Disord. 2020 Feb;25(1):143-150. doi: 10.1007/s40519-018-0531-0. Epub 2018 Jul 10. PMID: 29987777
32. Newly diagnosed type 2 diabetes may serve as a potential marker for pancreatic cancer.  Dankner R, Freedman LS, Gerstein HC, Roth J, Keinan-Boker L. Diabetes Metab Res Rev. 2018 Sep;34(6):e3018. doi: 10.1002/dmrr.3018. Epub 2018 Jun 17. PMID: 29673046
33. Implementation of a competency-based medical education approach in public health and epidemiology training of medical students. Dankner R, Gabbay U, Leibovici L, Sadeh M, Sadetzki S. Isr J Health Policy Res. 2018 Feb 20;7(1):13. doi: 10.1186/s13584-017-0194-8. PMID: 29463297
34. Lessons learned from the 1-hour post-load glucose level during OGTT: Current screening recommendations for dysglycaemia should be revised. Bergman M, Jagannathan R, Buysschaert M, Pareek M, Olsen MH, Nilsson PM, Medina JL, Roth J, Chetrit A, Groop L, Dankner R. Diabetes Metab Res Rev. 2018 Jul;34(5):e2992. doi: 10.1002/dmrr.2992. Epub 2018 Mar 24. PMID: 29460410
35. Symptoms of depression and anxiety and 11-year all-cause mortality in men and women undergoing coronary artery bypass graft (CABG) surgery. Geulayov G, Novikov I, Dankner D, Dankner R. J Psychosom Res. 2018 Feb;105:106-114. doi: 10.1016/j.jpsychores.2017.11.017. Epub 2017 Dec 1. PMID: 29332626
36. New onset diabetes in adulthood is associated with a substantial risk for mortality at all ages: a population based historical cohort study with a decade-long follow-up. Zucker I, Shohat T, Dankner R, Chodick G. Cardiovasc Diabetol. 2017 Aug 15;16(1):105. doi: 10.1186/s12933-017-0583-x. PMID: 28810857
37. Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis.  Paige E, Barrett J, Pennells L, Sweeting M, Willeit P, Di Angelantonio E, Gudnason V, Nordestgaard BG, Psaty BM, Goldbourt U, Best LG, Assmann G, Salonen JT, Nietert PJ, Verschuren WMM, Brunner EJ, Kronmal RA, Salomaa V, Bakker SJL, Dagenais GR, Sato S, Jansson JH, Willeit J, Onat A, de la Cámara AG, Roussel R, Völzke H, Dankner R, Tipping RW, Meade TW, Donfrancesco C, Kuller LH, Peters A, Gallacher J, Kromhout D, Iso H, Knuiman M, Casiglia E, Kavousi M, Palmieri L, Sundström J, Davis BR, Njølstad I, Couper D, Danesh J, Thompson SG, Wood A. Am J Epidemiol. 2017 Oct 15;186(8):899-907. doi: 10.1093/aje/kwx149. PMID: 28549073
38. Reducing the prevalence of dysglycemia: is the time ripe to test the effectiveness of intervention in high-risk individuals with elevated 1 h post-load glucose levels?  Bergman M, Jagannathan R, Buysschaert M, Medina JL, Sevick MA, Katz K, Dorcely B, Roth J, Chetrit A, Dankner R. Endocrine. 2017 Mar;55(3):697-701. doi: 10.1007/s12020-017-1236-2. Epub 2017 Jan 25. PMID: 28124259